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These multiple follicles can be taken out by oocyte retrieval (egg collection) for use in in vitro fertilisation (IVF), or be given time to ovulate, resulting in superovulation which is the ovulation of a larger-than-normal number of eggs, [2] generally in the sense of at least two.
Primordial follicle initiation and development varies by species; in the canine primordial follicle formation occurs 17–54 days post birth. At 17 days, primordial follicles, each of consists of a small oocyte (with no zona pellucida) and a single layer of flattened pre-granulosa cells, can first be observed in the cortical layer of the ovary.
There are a limited number of non-surgical fertility control options available for cats and dogs, which vary in effectiveness, duration of action and safety. Progestin contraceptives are approved for contraception in male and female dogs and cats in multiple countries. Typically approval is for a few months of use.
Transvaginal oocyte retrieval is more properly referred to as transvaginal ovum retrieval when the oocytes have matured into ova, as is normally the case in IVF. It can be also performed for egg donation , oocyte cryopreservation and other assisted reproduction technology such as ICSI .
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There are different options for hormones and medicines that can be used to trigger maturation of the oocytes prior to a planned egg retrieval that help reduce risk as well.”
Growth of follicles can be seen in subsequent autografts, mature eggs can be retrieved and IVF carried out making it a good candidate for fertility preservation. Drug free IVA may alternatively be used. This is the same as IVA however no drugs are used to stimulate the Atk pathway, only ovarian cortex fragmentation is used. [3]
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