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Selenium is a component of the amino acids selenocysteine and selenomethionine. In humans, selenium is a trace element nutrient that functions as cofactor for glutathione peroxidases and certain forms of thioredoxin reductase. [1] Selenium-containing proteins are produced from inorganic selenium via the intermediacy of selenophosphate (PSeO 3 3 ...
A 2011 study based on the trial found that the risk of prostate cancer was elevated by 17% in the group that took vitamin E supplements, which was statistically significant. [8] [13] A 2014 study based on SELECT data found that selenium supplementation increased the risk of high-grade prostate cancer in men who had a higher baseline selenium ...
Selenium deficiency occurs when an organism lacks the required levels of selenium, a critical nutrient in many species.Deficiency, although relatively rare in healthy well-nourished individuals, [1] can have significant negative results, [2] affecting the health of the heart and the nervous system; contributing to depression, anxiety, and dementia; and interfering with reproduction and gestation.
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
At just 19 years old, Eldiara Doucette — known on social media as "Bionic Barbie" — was diagnosed with synovial sarcoma, a rare form of soft tissue cancer that affects only 1,000 people per ...
This gene encodes a member of the glutathione peroxidase family, consisting of eight known glutathione peroxidases (GPx1-8) in humans. Mammalian Gpx1 (this gene), Gpx2, Gpx3, and Gpx4 have been shown to be selenium-containing enzymes, whereas Gpx6 is a selenoprotein in humans with cysteine-containing homologues in rodents.
MDA-MB-231 cells were derived from a pleural effusion due to an adenocarcinoma originating in a 51-year-old caucasian female. [2] The cell line is triple negative, meaning it lacks oestrogen receptors, progesterone receptors, and HER2 (human epidermal growth factor receptor 2) amplification which many current treatment options rely on making it difficult to cure.
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