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The newest weight-loss drugs, Wegovy and Zepbound, are incredibly popular. But doctors are still learning about all of the ways they affect the body—both helpful and harmful—beyond reducing ...
Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
The first study to assess how weight-loss drugs affect the whole of human health has discovered an "eye-opening" impact on the body, researchers say. ... published in the journal Nature Medicine ...
As of 2023, Annual Review of Pharmacology and Toxicology is being published as open access, under the Subscribe to Open model. [1] As of 2024, Journal Citation Reports lists the journal's 2023 impact factor as 11.2, ranking it second of 106 journal titles in the category "Toxicology" and ninth of 354 titles in the category "Pharmacology ...
Drug-drug interactions can be of serious concern for patients who are undergoing multi-drug therapies. [5] Coadministration of chloroquine , an anti-malaria drug, and statins for treatment of cardiovascular diseases has been shown to cause inhibition of organic anion-transporting polypeptides (OATPs) and lead to systemic statin exposure.
But clinical trials are artificial environments: In the real world, 37% of people using a GLP-1 drug for either diabetes or weight loss had quit a year after starting, according to 2024 research ...
Expert Opinion on Drug Metabolism & Toxicology is a monthly peer-reviewed medical journal publishing review articles on ADME-Tox. It was established in 2005 and is published by Taylor and Francis. The editor-in-chief is Luis Valerio (Food and Drug Administration).
Researchers found that patients who got the highest dose of the drug lost on average 15.6% of their body weight after 48 weeks, compared to the 2.2% body weight loss seen in patients who got a ...