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Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). These patients have lancinating nerve root pain which is aggravated by coughing, and features of sensory ataxia with ocular ...
Pel also discovered what came to be called "Pel's crisis," defined as "Ocular crises in tabes dorsalis, characterized by neuralgic paroxysmal pains affecting the eyes and the ophthalmic area(s)." The term "Pel's crisis", however, is no longer commonly used, in favor of "tabetic ocular crisis". [4]
Tabes dorsalis is a form of late neurosyphilis that affects the posterior columns of the spinal cord. Parenchymal syphilis occurs in the late stage of neurosyphilis, with average presentation occurring 15 to 25 years after initial infection. [3] This stage of the disease is generally in the form of tabes dorsalis or general paresis.
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
Abadie's sign of tabes dorsalis is a medical sign of tabes dorsalis, a late consequence of neurosyphilis. It is elicited by compressing the Achilles tendon , which normally causes pain. A positive Abadie's sign is defined by the absence of pain.
It is often a symptom of tabes dorsalis, which is a key finding in tertiary syphilis. It is caused by degeneration of the posterior (dorsal) white column of the spinal cord. In popular culture
Among his scientific publications was Der Augenbefund in seiner diagnostischen und differentialdiagnostischen Bedeutung bei Tabes dorsalis, Lues cerebrospinalis, Multipler Sklerose (1936), [2] a neuro-ophthalmological analysis of eye disorders and their differential diagnostic relevance in tabes dorsalis, lues cerebrospinalis and multiple sclerosis.
Babinski–Vaquez syndrome: Tabes dorsalis associated with cardiac and arterial pathology as late manifestation of syphilis. Named with hematologist Louis Henri Vaquez. Babinski–Weil test: Test for demonstration of a laterodeviation in case of vestibular disorders. Named with neurologist Mathieu-Pierre Weil.