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Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
Pseudoephedrine has been studied in the treatment of snoring. [185] However, data are inadequate to support this use. [185] A study has found that pseudoephedrine can reduce milk production in breastfeeding women. [186] [187] This might have been due to suppression of prolactin secretion. [187] Pseudoephedrine might be useful for lactation ...
[30] [32] Asthma treatment recommendations during pregnancy are similar to those in non-pregnant women. [33] As of 2018, Asthma was the most prevalent respiratory disorder to complicate pregnancy, remaining a high-risk condition despite therapeutic advancements. [34]
Phenylephrine is an over-the-counter drug that has been used for decades to relieve congestion and stuffy nose caused by allergies or colds, and purportedly works by reducing the swelling of blood ...
Treatment of this condition is very similar to treatment of non-gravid heart failure patients, however, safety of the fetus must be prioritized. For example, for anticoagulation due to increased risk for thromboembolism, low molecular weight heparin which is safe for use during pregnancy is used instead of warfarin which crosses the placenta. [37]
[9] [1] [10] [11] It was previously commonly used in prescription and over-the-counter cough and cold preparations. The medication is taken by mouth. [4] [12] Side effects of phenylpropanolamine include increased heart rate and blood pressure, among others. [13] [14] [15] [12] Rarely, phenylpropanolamine has been associated with hemorrhagic stroke.
Phenylephrine is an oral medication primarily used as a decongestant. [5] [6] It is a selective α 1-adrenergic receptor activator which results in the constriction of both arteries and veins. [5] Common side effects include nausea, headache, and anxiety. [5] Phenylephrine was patented in 1927 and came into medical use in 1938. [7]
As inhalers they are used to treat asthma, as nasal sprays to treat hay fever (allergic rhinitis) and as eye drops for allergic conjunctivitis. [2] Finally, in oral form, they are used to treat the rare condition of mastocytosis .