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Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
[1] [22] A closely related sympathomimetic and decongestant, phenylpropanolamine, was withdrawn due to associations with markedly increased blood pressure and incidence of hemorrhagic stroke. [22] There has been concern that pseudoephedrine may likewise dangerously increase blood pressure and thereby increase the risk of stroke, whereas others ...
Treatment of this condition is very similar to treatment of non-gravid heart failure patients, however, safety of the fetus must be prioritized. For example, for anticoagulation due to increased risk for thromboembolism, low molecular weight heparin which is safe for use during pregnancy is used instead of warfarin which crosses the placenta. [37]
Common side effects include trouble sleeping, anxiety, headache, hallucinations, high blood pressure, fast heart rate, loss of appetite, and urinary retention. [11] Serious side effects include stroke and heart attack. [11] While probably safe in pregnancy, its use in this population [citation needed] is poorly studied.
[9] [1] [10] [11] It was previously commonly used in prescription and over-the-counter cough and cold preparations. The medication is taken by mouth. [4] [12] Side effects of phenylpropanolamine include increased heart rate and blood pressure, among others. [13] [14] [15] [12] Rarely, phenylpropanolamine has been associated with hemorrhagic stroke.
Phenylephrine is an over-the-counter drug that has been used for decades to relieve congestion and stuffy nose caused by allergies or colds, and purportedly works by reducing the swelling of blood ...
Phenylephrine is an oral medication primarily used as a decongestant. [5] [6] It is a selective α 1-adrenergic receptor activator which results in the constriction of both arteries and veins. [5] Common side effects include nausea, headache, and anxiety. [5] Phenylephrine was patented in 1927 and came into medical use in 1938. [7]
PSD has a reported incidence of 18% to 33%, though it is commonly underdiagnosed due to overlapping symptoms between stroke and depression. [3] A comprehensive meta-analysis found that over half of stroke patients experience at least one episode of depression. [4] Various risk factors increase the likelihood of developing PSD, including: [3] [4 ...