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Mouse Embryonic Fibroblasts (MEFs) are a type of fibroblast prepared from mouse embryo. MEFs show a spindle shape when cultured in vitro, a typical feature of fibroblasts. The MEF is a limited cell line. After several transmissions, MEFs will senesce and finally die off.
The primary mouse embryonic fibroblast cells were transferred (the "T") every 3 days (the first "3"), and inoculated at the rigid density of 3 × 10 5 cells per 20 cm 2 dish (the second "3") continuously. [2] The spontaneously immortalized cells with stable growth rate were established after 20 to 30 generations in culture, and then named '3T3 ...
A fibroblast is a type of biological cell typically with a spindle shape [1] that synthesizes the extracellular matrix and collagen, [2] ... Mouse embryonic ...
2249 14175 Ensembl ENSG00000075388 ENSMUSG00000050917 UniProt P08620 P11403 RefSeq (mRNA) NM_002007 NM_010202 RefSeq (protein) NP_001998 NP_034332 Location (UCSC) Chr 11: 69.77 – 69.78 Mb Chr 7: 144.4 – 144.42 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fibroblast growth factor 4 is a protein that in humans is encoded by the FGF4 gene. The protein encoded by this gene is a ...
Fibroblast growth factor 15 is a protein in mouse encoded by the Fgf15 gene. [1] It is a member of the fibroblast growth factor (FGF) family but, like FGF19, FGF21 and FGF23, has endocrine functions. FGF19 is the orthologous protein in humans. They are often referred together as FGF15/19. [2] [3]
Human iPS cells colonies. The spindle-shaped cells in the background are mouse fibroblast cells. Only those cells comprising the center colony are human iPS cells. Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell.
2255 14165 Ensembl ENSG00000070193 ENSMUSG00000021732 UniProt O15520 O35565 RefSeq (mRNA) NM_004465 NM_008002 RefSeq (protein) NP_004456 NP_032028 Location (UCSC) Chr 5: 44.3 – 44.39 Mb Chr 13: 118.81 – 118.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. Function The protein encoded by this ...
Differentiated adipocytes in a 3T3-L1 cell line stained with Oil Red O. 3T3-L1 is a sub clonal cell line derived from the original 3T3 Swiss albino cell line of 1962. The 3T3 original cell line was isolated from a mouse embryo and propagated for this specific line of 3T3 cells is used to study adipose tissue-related diseases and dysfunctions.