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Polymyxin B/trimethoprim, sold under the brand name Polytrim is an antimicrobial solution for topical ophthalmic use in the treatment of acute bacterial conjunctivitis and blepharoconjunctivitis. [1] In 2022, it was the 252nd most commonly prescribed medication in the United States, with more than 1 million prescriptions. [2] [3]
The mechanism by which the bacteria causes symptoms of blepharitis is not fully understood and may include direct irritation of bacterial toxins and/or enhanced cell-mediated immunity to S. aureus. Staphylococcal blepharitis is caused by an infection of the anterior portion of the eyelid by Staphylococcal bacteria. [14]
An eye with bacterial conjunctivitis. Bacteria are responsible for approximately 70% of conjunctivitis in children and less than 20% of cases in adults. [7] Common bacteria responsible for bacterial conjunctivitis are Staphylococcus including Staph aureus, Streptococcus such as strep pneumoniae, [10] Haemophilus species and Moraxella ...
Besifloxacin is a fluoroquinolone that has a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-negative ocular pathogens: e.g., Corynebacterium pseudodiphtheriticum, Moraxella lacunata, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis, Streptococcus mitis, Streptococcus oralis, Streptococcus pneumoniae and Streptococcus salivarius.
"Conjunctivitis basically means inflammation of the conjunctiva, which is the clear part that covers the white part of the eyes," says Dr. Sumitra Khandelwal, an associate professor of ...
The SPC is not intended to give general advice about treatment of a condition but does state how the product is to be used for a specific treatment. It forms the basis of information for health professionals to know how to use the specific product safely and effectively. The package leaflet supplied with the product is aimed at end-users. [3]
Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. [5] This includes use as an eye ointment to treat conjunctivitis. [6] By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. [5]
Moraxella lacunata was first described independently by Victor Morax (1896) and Theodor Axenfeld (1897), hence the alternate name "Morax-Axenfeld diplobacilli" and the name of eye infection in humans is sometimes called Morax-Axenfeld conjunctivitis.