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Bone Marrow Transplantation is a peer-reviewed medical journal covering transplantation of bone marrow in humans. It is published monthly by Nature Research . The scope of the journal includes stem cell biology , transplantation immunology , translational research , and clinical results of specific transplant protocols.
Thomas and his wife and research partner Dottie Thomas developed bone marrow transplantation as a treatment for leukemia. Thomas was a lead investigator in a failed series of experimental treatments for leukemia and for Graft-versus-host disease at Seattle's Fred Hutchinson Cancer Research Center from 1981 to 1993.
The most commonly used source of MSC's is bone marrow aspirate. Most of the adult bone marrow consists of blood cells in various stages of differentiation. [10] These marrow components can be divided into plasma, red blood cells, platelets, and nucleated cells. The adult stem cell fraction is present in the nucleated cells of the marrow.
The world-renowned "second" Berlin patient, Timothy Ray Brown, had a bone marrow transplant on February 7, 2007, to cure his leukemia, and hopefully his HIV. The results of the procedure were presented by Dr. Gero Hütter at the CROI 2008 Conference in Boston. [ 8 ]
From 1980 to 1997, Gale was Chairman of the Scientific Advisory Committee of the Center for International Blood and Marrow Transplant Research (CIBMTR), an organization of more than 400 transplant centers in over 60 countries worldwide working together to analyze and advance knowledge about blood cell and bone marrow transplants. From 1989 to ...
[2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood. Research is underway to develop various sources for stem cells as well as to apply stem-cell treatments for neurodegenerative diseases [4] and conditions such as diabetes and heart disease.
A bone marrow harvest in progress The preferred sites for the procedure. In a bone marrow transplant, hematopoietic stem cells are removed from a person and infused into another person or into the same person at a later time . If the donor and recipient are compatible, these infused cells will then travel to the bone marrow and initiate blood ...
Dorothy "Dottie" Thomas (née Martin) (San Antonio, Texas, September 18, 1922 – Seattle, January 9, 2015) was an American hematology researcher and administrator known for her work in developing bone marrow transplants.
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