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Mometasone, also known as mometasone furoate, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma. [ 10 ] [ 11 ] [ 12 ] Specifically it is used to prevent rather than treat asthma attacks. [ 10 ]
Mometasone/formoterol, sold under the brand name Dulera among others, is a fixed-dose combination medication used in the long-term treatment of asthma. [1] It contains mometasone a steroid and formoterol a long-acting beta agonist. [1] It is only recommended in those for whom an inhaled steroid is not sufficient. [1] It is used by inhalation. [1]
2-Furoyl chloride is an acyl chloride of furan.It takes the form of a corrosive liquid, which is more irritating to the eyes than benzoyl chloride. [1] 2-Furoyl chloride is a useful pharmaceutical intermediate and is used in the synthesis of mometasone furoate, an antiinflammatory prodrug used in the treatment of skin disorders, hay fever and asthma.
[1] [2] [3] It contains olopatadine hydrochloride and mometasone furoate monohydrate. [1] [2] It is sprayed into the nose. [1] [2] Common side effects include an unpleasant taste . [1] It was approved for medical use in Australia in December 2019, [1] [4] and in the United States in January 2022. [2]
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Flumetasone is classified as a moderately potent corticosteroid and a glucocorticoid receptor agonist.Like other corticosteroids, it functions as an immunosuppressant by decreasing function of the lymphatic system, reducing immunoglobulin and complement concentrations, lowering lymphocyte concentrations, and preventing antigen-antibody binding. [2]
Fluticasone furoate/vilanterol, sold under the brand name Breo Ellipta among others, is a combination medication for the treatment of chronic obstructive pulmonary disease (COPD) and asthma. [3] It contains fluticasone furoate , an inhaled corticosteroid , and vilanterol , an ultra- long-acting β 2 agonist (ultra-LABA).
[1] [2] [3] In addition to its potent corticosteroid activity, fluorometholone acetate is a progestogen. [ 4 ] It has been studied in the treatment of breast cancer in women and has been found to be effective, producing remission in about 20% of women with advanced breast cancer at an oral dosage of 50 mg/day. [ 4 ]