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Post-exposure prophylaxis, also known as post-exposure prevention (PEP), is any preventive medical treatment started after exposure to a pathogen in order to prevent the infection from occurring. It should be contrasted with pre-exposure prophylaxis , which is used before the patient has been exposed to the infective agent.
It was initially attempted in 2004 on Jeanna Giese, a teenage girl from Wisconsin, who subsequently became the first human known to have survived rabies without receiving post-exposure prophylaxis before symptom onset. [100] [101] Giese did require extensive rehabilitation afterward, and her balance and neural function remained impaired. [102]
On a global scale, however, the World Health Organization reports that dogs are the main source of human rabies deaths, contributing up to 99% of all rabies transmissions to humans.
The purified Vero cell rabies vaccine uses the attenuated Wistar strain of the rabies virus, and uses the Vero cell line as its host. CCEEVs can be used in both pre- and post-exposure vaccinations. CCEEVs use inactivated rabies virus grown from either embryonated eggs or in cell cultures and are safe for use in humans and animals. [11] [24]
After the first course, or the "Day 0" dose of rabies vaccination, follow-up rabies vaccinations are given on Days 3, 7, and 14 from exposure. Those shots are given in the deltoid muscle ...
The two kittens had been with one that later turned out to have rabies. The kittens were being taken care of at Summit School at Nyack. Rabies in Rockland: 2 kittens test negative; 98 get vaccines ...
Rabies immunoglobulin (RIG) is a medication made up of antibodies against the rabies virus. [10] It is used to prevent rabies following exposure. [10] It is given after the wound is cleaned with soap and water or povidone-iodine and is followed by a course of rabies vaccine. [10] It is given by injection into the site of the wound and into a ...
The treatments used for the prevention of rabies, (post-exposure prophylaxis, and pre-exposure prophylaxis) can be high in price, and this may be another contributing factor to the high percentage of rabies infections from in Africa, and similar countries that do not have the vaccines and treatments readily available. [42]