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Sucralfate is a locally acting substance that in an acidic environment (pH < 4) reacts with hydrochloric acid in the stomach to form a cross-linking, viscous, paste-like material capable of acting as an acid buffer for as long as 6 to 8 hours after a single dose. [29]
Sucralfate is a mucosal coating agent, composed of an aluminum salt of sulfated sucrose. [97] It is not recommended for use in the prevention of oral mucositis in head and neck cancer patients receiving radiotherapy or chemoradiation , due to a lack of efficacy found in a well-designed, randomized controlled trial .
Gastric cytoprotective drugs include carbenoxolone, deglycyrrhizinised liquorice, sucralfate (aluminium hydroxide and sulphated sucrose), misoprostol (a prostaglandin analogue), bismuth chelate (tri-potassium di-citrato bismuthate) and zinc L-carnosine.
Sucrose octaacetate is a chemical compound with formula C 28 H 38 O 19 or (C 2 H 3 O 2) 8 (C 12 H 14 O 3), an eight-fold ester of sucrose and acetic acid.Its molecule can be described as that of sucrose C
English: Skeletal formula of sucralfate—a cytoprotective medication used in the treatment of GERD, gastritis, peptic ulcer disease, stress ulcers and dyspepsia. Date 22 September 2023
From Wikipedia, the free encyclopedia. ... Sucralfate; From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) ...
Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. [2] Misoprostol and other prostaglandin analogues protect the lining of the gastrointestinal tract from harmful stomach acid and are especially indicated for the elderly on continuous doses of NSAIDs.
Gastritis is the inflammation of the lining of the stomach. [1] It may occur as a short episode or may be of a long duration. [1] There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain (see dyspepsia). [1]