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The Broselow Tape relates a child's height as measured by the tape to their weight to provide medical instructions including medication dosages, the size of the equipment that should be used, and the level of energy when using a defibrillator. Particular to children is the need to calculate all these therapies for each child individually.
Bromocriptine, originally marketed as Parlodel and subsequently under many brand names, [1] is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease, hyperprolactinaemia, neuroleptic malignant syndrome, and, as an adjunct, type 2 diabetes.
Absorption of bromocriptine oral dose is approximately 28%; however, only 6% reaches the systemic circulation unchanged, due to a substantial first-pass effect. Bromocriptine reaches mean peak plasma levels after about 1–1.5 hours after a single oral dose. The drug has high protein binding, ranging from 90-96% bound to serum albumin.
One treatment often used is a dose of a corticosteroid at the beginning of each fever episode. [4] A single dose usually ends the fever within several hours. [4] However, in some children, they can cause the fever episodes to occur more frequently. [4] Interleukin-1 inhibition appears to be effective in treating this condition. [5]
Medications used include dantrolene, bromocriptine, and diazepam. [2] The risk of death among those affected is about 10%. [4] Rapid diagnosis and treatment is required to improve outcomes. [1] Many people can eventually be restarted on a lower dose of antipsychotic. [2] [3]
Children with febrile convulsions are more likely to have a febrile seizure in the future if they were young at their first seizure (less than 18 months old), have a family history of a febrile convulsions in first-degree relatives (a parent or sibling), have a short time between the onset of fever and the seizure, had a low degree of fever ...
Periodic fever syndromes are a set of disorders characterized by recurrent episodes of systemic and organ-specific inflammation.Unlike autoimmune disorders such as systemic lupus erythematosus, in which the disease is caused by abnormalities of the adaptive immune system, people with autoinflammatory diseases do not produce autoantibodies or antigen-specific T or B cells.
The most common symptoms are fever, intense headache, vomiting and neck stiffness and occasionally photophobia. [1] Other symptoms include confusion or altered consciousness, nausea, and an inability to tolerate light or loud noises. [1] Young children often exhibit only nonspecific symptoms, such as irritability, drowsiness, or poor feeding. [1]