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Usage of aspirin for pain relief during pregnancy is not recommended. Aspirin use during pregnancy has not demonstrated an increased risk of spontaneous abortion within the early weeks of pregnancy. However, its usage during organogenesis and the third trimester can lead to elevated risk of intrauterine growth retardation and maternal ...
Taking acetaminophen during pregnancy has been associated with an increased risk of autism, and ADHD in children in some research. A new study suggests that it is not acetaminophen that is linked ...
A 2014 study [23] found that "Maternal acetaminophen use during pregnancy is associated with a higher risk for HKDs and ADHD-like behaviors in children." The study was the first of its kind, and concluded that, "because the exposure and outcome are frequent, these results are of public health relevance but further investigations are needed."
Typically the pain only lasts for a few seconds. During pregnancy, the growing uterus can put stress on the round ligament of the uterus, causing it to stretch and lead to pain. Paracetamol (acetaminophen) is the recommended pain reliever for pregnant women with round ligament pain.
In contrast, paracetamol (acetaminophen) is regarded as being safe and well tolerated during pregnancy, but Leffers et al. released a study in 2010, indicating that there may be associated male infertility in the unborn. [92] [93] Doses should be taken as prescribed, due to risk of liver toxicity with overdoses. [94]
One meta-analysis indicated that ibuprofen is more effective than acetaminophen in children at similar doses when both are given alone. [16] Due to concerns about Reye syndrome, it is recommended that aspirin and combination products that contain aspirin not be given to children or teenagers during episodes of fever-causing illnesses. [17] [18]
The association between paracetamol use and asthma in children has been a matter of controversy. [85] However, the most recent research suggests that there is no association, [86] and that the frequency of asthma exacerbations in children after paracetamol is the same as after another frequently used pain killer, ibuprofen. [60]
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature.