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Crisaborole (chemical name: 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile) is a member of the class of benzoxaboroles characterized by the presence of a boronic acid hemiester with a phenolic ether and a nitrile. [7] Crisaborole crystallizes into two polymorphs that differ in the
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.
Mayo Clinic Proceedings is a monthly peer-reviewed medical journal published by Elsevier and sponsored by the Mayo Clinic.It covers the field of general internal medicine.The journal was established in 1926 as the Proceedings of the Staff Meetings of the Mayo Clinic and obtained its current name in 1964.
Progressive inflammatory neuropathy is a autoimmune disease that was identified in a report, released on January 31, 2008, by the Centers for Disease Control and Prevention. [1] The first known outbreak of this neuropathy occurred in southeastern Minnesota in the United States .
Chronic relapsing inflammatory optic neuropathy (CRION) is a form of recurrent optic neuritis that is steroid responsive and dependent. [1] Patients typically present with pain associated with visual loss. [1] CRION is a clinical diagnosis of exclusion, and other demyelinating, autoimmune, and systemic causes should be ruled out. [3]
Peripheral neuropathy and mononeuropathy are common neurological disorders, with a diverse range of variables and causes to conclude a diagnosis. [2] Neuropathy has three sub-classifications; mononeuropathy is a result of an entrapped or traumatised nerve or nerve area, Mononeuropathy multiplex is linked to chronic diseases like leprosy, and ...
Anti-MAG peripheral neuropathy is a specific type of peripheral neuropathy in which the person's own immune system attacks cells that are specific in maintaining a healthy nervous system. As these cells are destroyed by antibodies , the nerve cells in the surrounding region begin to lose function and create many problems in both sensory and ...
Neuropathy can be due to chronic high blood sugar levels (diabetic neuropathy). These drugs also reduce pain from viruses such as shingles, phantom limb pain and post-stroke pain. [ 74 ] These mechanisms vary and in general are more effective in neuropathic pain disorders as well as complex regional pain syndrome . [ 75 ]