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The partial thromboplastin time (PTT), also known as the activated partial thromboplastin time (aPTT or APTT), is a blood test that characterizes coagulation of the blood.A historical name for this measure is the Kaolin-cephalin clotting time (KCCT), [1] reflecting kaolin and cephalin as materials historically used in the test.
Clotting time is a general term for the time required for a sample of blood to form a clot, or, in medical terms, coagulate. The term "clotting time" is often used when referring to tests such as the prothrombin time (PT) , activated partial thromboplastin time (aPTT or PTT), activated clotting time (ACT), thrombin time (TT), or Reptilase time .
The basic purpose of these tests is to determine the cause of prolongation of Prothrombin Time (PT), Partial Thromboplastin Time, or sometimes of thrombin time (TT). Mixing studies take advantage of the fact that factor levels that are 50 percent of normal should give a normal Prothrombin time (PT) or Partial thromboplastin time (PTT) result. [2]
Activated partial thromboplastin time (APTT or aPTT) Characteristics of the velocity of passage of the intrinsic coagulation pathway; Poor plasma (the most convenient to work with, but no realization of the thrombocyte clotting mechanism) Contact activation pathway
Liver function tests (LFTs or LFs), also referred to as a hepatic panel or liver panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin , bilirubin (direct and indirect), and others.
The INR is a corrected ratio of a patient's PT to normal Activated partial thromboplastin time (APTT) 18, [15] 30 [5] [18] 28, [15] 42, [5] 45 [18] s: Thrombin clotting time (TCT) 11: 18: s: Fibrinogen: 1.7, [15] 2.0 [5] 3.6, [5] 4.2 [15] g/L: Antithrombin: 0.80 [5] 1.2 [5] kIU/L: 0.15, [151] 0.17 [152] 0.2, [151] 0.39 [152] mg/mL Bleeding time ...
Activated clotting time (ACT), also known as activated coagulation time, is a test of coagulation. [1] [2]The ACT test can be used to monitor anticoagulation effects, such as from high-dose heparin before, during, and shortly after procedures that require intense anticoagulant administration, such as cardiac bypass, interventional cardiology, thrombolysis, extra-corporeal membrane oxygenation ...
Normal values for thrombin time may be 12 to 14 seconds, [6] but the test has significant reagent variability. If batroxobin is used, the time should be between 15 and 20 seconds. Thrombin time can be prolonged by heparin, fibrin degradation products, and fibrinogen deficiency or abnormality.