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Acute kidney injury, shock, septic shock, sepsis, multiple organ failure. In immunology, systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body. [1] It is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually ...
3 million per year [1] Acute respiratory distress syndrome (ARDS) is a type of respiratory failure characterized by rapid onset of widespread inflammation in the lungs. [1] Symptoms include shortness of breath (dyspnea), rapid breathing (tachypnea), and bluish skin coloration (cyanosis). [1] For those who survive, a decreased quality of life is ...
Respiratory burst (or oxidative burst) is the rapid release of the reactive oxygen species (ROS), superoxide anion (O−. 2) and hydrogen peroxide (H. 2O. 2), from different cell types. This is usually utilised for mammalian immunological defence, but also plays a role in cell signalling. Respiratory burst is also implicated in the ovum of ...
Asthma is a long-term inflammatory disease of the airways of the lungs. [ 4 ] It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. [ 9 ][ 10 ] Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. [ 3 ]
Inflammation, such as that caused by sepsis, causes endothelial cell dysfunction, fluid leakage from capillaries and impairs drainage of fluid from the lungs. Elevated inspired oxygen concentration often becomes necessary at this stage, and may facilitate a 'respiratory burst' in immune cells. In a secondary phase, endothelial cell dysfunction ...
Specialty. Pulmonology. Asthma is a common pulmonary condition defined by chronic inflammation of respiratory tubes, tightening of respiratory smooth muscle, and episodes of bronchoconstriction. [1] The Centers for Disease Control and Prevention estimate that 1 in 11 children and 1 in 12 adults have asthma in the United States of America. [1]
Inflammation (from Latin: inflammatio) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. [1][2] The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa). Inflammation is a generic response, and ...
The primary cause triggers an uncontrolled inflammatory response. [citation needed] Sepsis is the most common cause of multiple organ dysfunction syndrome and may result in septic shock. In the absence of infection, a sepsis-like disorder is termed systemic inflammatory response syndrome (SIRS). Both SIRS and sepsis could ultimately progress to ...