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A demyelinating disease refers to any disease affecting the nervous system where the myelin sheath surrounding neurons is damaged. [ 1 ] This damage disrupts the transmission of signals through the affected nerves, resulting in a decrease in their conduction ability. Consequently, this reduction in conduction can lead to deficiencies in ...
Remyelination is the process of propagating oligodendrocyte precursor cells to form oligodendrocytes to create new myelin sheaths on demyelinated axons in the Central nervous system (CNS). This is a process naturally regulated in the body and tends to be very efficient in a healthy CNS. [1] The process creates a thinner myelin sheath than ...
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.
Neuroregeneration involves the regrowth or repair of nervous tissues, cells or cell products. Neuroregenerative mechanisms may include generation of new neurons, glia, axons, myelin, or synapses. Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms involved ...
Myelin (/ ˈmaɪ.əlɪn / MY-ə-lin) is a lipid -rich material that surrounds nerve cell axons (the nervous system's electrical wires) to insulate them and increase the rate at which electrical impulses (called action potentials) pass along the axon. [ 1 ][ 2 ] The myelinated axon can be likened to an electrical wire (the axon) with insulating ...
Brain healing is the process that occurs after the brain has been damaged. If an individual survives brain damage, the brain has a remarkable ability to adapt. When cells in the brain are damaged and die, for instance by stroke, there will be no repair or scar formation for those cells. The brain tissue will undergo liquefactive necrosis, and a ...
Causes. CNS demyelination autoimmune disease causes the myelin sheath to deteriorate since the sense of recognition of self is lost. The loss of the myelin insulation either disrupts or prevents neural conduction along the nerve cell's axon.
Specialty. Neurology. Leukodystrophies are a group of, usually, inherited disorders, characterized by degeneration of the white matter in the brain. [ 1 ] The word leukodystrophy comes from the Greek roots leuko, "white", dys, "abnormal" and troph, "growth". The leukodystrophies are caused by imperfect growth or development of the glial cells ...