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A lipoma is a benign tumor made of fat tissue. [ 1 ] They are generally soft to the touch, movable, and painless. [ 1 ] They usually occur just under the skin, but occasionally may be deeper. [ 1 ] Most are less than 5 cm (2.0 in) in size. [ 2 ] Common locations include upper back, shoulders, and abdomen. [ 4 ]
Lipomatosis is believed to be an autosomal dominant condition in which multiple lipomas are present on the body. Many discrete, encapsulated lipomas form on the trunk and extremities, with relatively few on the head and shoulders. [1] In 1993, a genetic polymorphism within lipomas was localized to chromosome 12q15, where the HMGIC gene encodes ...
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [ 2 ][ 7 ] These contrast with benign tumors, which do not spread. [ 7 ] Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. [ 1 ]
Familial multiple lipomatosis is a hereditary adipose tissue disorder that is characterized by the formation of multiple lipomas that occur in a particular distribution. [1] The lipomas are well-encapsulated, slow-growing, benign fatty tumors. The distribution is defined as being focused in the trunk of the body and extremities. [2]
The tumor is the pale, crab-shaped mass at the center, surrounded by normal, yellow fatty tissue. Some hormones play a role in the development of cancer by promoting cell proliferation . [ 58 ] Insulin-like growth factors and their binding proteins play a key role in cancer cell growth, differentiation and apoptosis , suggesting possible ...
Dercum's disease. Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat from scalp to plantar surface of the foot. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has ...
The white tumor infiltrates the adjacent skeletal muscle (red tissue – lower left) and fat (yellow tissue – upper left). This tendency for invasion of adjacent normal tissues and structures is the reason that desmoid-type fibromatosis has a relatively high rate of local recurrence, even after surgical removal.
Lipoblastoma is a type of rare, subcutaneous, benign, fatty tumor, [ 1 ][ 2 ] found in infants, and children, more common in males with tendency of local recurrence. Local recurrence can happen in up to 80% of incompletely resected tumours. Therefore, complete surgical resection is required to prevent recurrence.