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Lactulose may be used to counter the constipating effects of opioids, and in the symptomatic treatment of hemorrhoids as a stool softener. [medical citation needed] Lactulose is commonly prescribed for children who develop fear of their bowel movements and are withholders.
Emollient laxatives, also known as stool softeners, are anionic surfactants that enable additional water and fats to be incorporated in the stool, making movement through the bowels easier. Properties. Site of action: small and large intestines; Onset of action: 12–72 hours; Examples: Docusate (Colace, Diocto), Gibs-Eze [3]
Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
Softener may refer to: Fabric softener , a conditioner that is typically applied to laundry during the rinse cycle in a washing machine. Stool softener , anionic surfactants that enable additional water and fats to be incorporated in the stool, making it easier for them to move through the gastrointestinal tract.
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Sodium picosulfate is a prodrug. [5] It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridyl)methane (DPM, BHPM).
It is used as stool stabilizer to treat constipation, diarrhea and abdominal discomfort. Bulk laxatives absorb liquid in the intestines and swell to form a soft bulky stool. The bulky mass stimulates the intestinal muscles, speeding stool transit time through the colon. Results usually occur within 12 to 72 hours.
Dulcolax Stool Softener, a trade name of dioctyl sodium sulfosuccinate, a common ingredient in products such as laxatives Dulcolax SP Drops, a trade name of sodium picosulfate , a stimulant laxative drug.