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Blood tests may show low levels of vitamin B 12, elevated levels of methylmalonic acid or homocysteine, and a routine complete blood counts may shows anemia with an elevated mean cell volume. [141] The presence of antibodies to gastric parietal cells and intrinsic factor may indicate pernicious anemia .
Symptoms “A B12 deficiency can cause physical and neurological symptoms, and research is also growing to support that it can also cause psychological issues as well,” says Shapiro.
Vitamin B 12 deficiency is a widespread condition that is particularly prevalent in populations with low or no consumption of animal foods. [9] Such diets can be due to a variety of reasons, such as low socioeconomic status or personal choice (i.e., veganism, vegetarianism).
Treatment using oral drugs is an easier option in management but the bioavailability of B12 is low. This is due to low absorption in the intestine, and breakdown by enzyme activity. Research continues to focus on the use of permeation enhancers or permeation absorbers in combination with the treatment.
An expert reveals why you shouldn't ignore symptoms of a B12 deficiency and what you can do to treat it.
Pernicious anaemia is a lifelong condition that affects nearly 5 in 100,000 people in the UK.
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