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Of them, 1,3,4-thiadiazole is the most common, appearing in such medications as cephazolin and acetazolamide. [ 1 ] [ 2 ] [ 3 ] In the Hurd-Mori reaction , an acyl hydrazone reacts with thionyl chloride or selenium dioxide to give a 1‑thia- or 1‑selena-2,3‑diazole.
1,2,3-benzothiadiazole is much less nucleophilic than naphthalene. Nitration is slow. [8] For that reason, many of its simple derivatives have been made from 2-aminothiophenols already having additional substituents. [7] 1,2,3-benzothiadiazole is a very weak base and alkylation reactions give exclusively the 3-amino quaternary salt. [9]
Thiazole (/ ˈ θ aɪ. ə z oʊ l /), or 1,3-thiazole, is a 5-membered heterocyclic compound that contains both sulfur and nitrogen. The term 'thiazole' also refers to a large family of derivatives. Thiazole itself is a pale yellow liquid with a pyridine-like odor and the molecular formula C 3 H 3 NS. [2]
1,2,5-thiadiazole. 1,3,4-thiadiazole. Use as antifungal agents. Skeletal formula of fluconazole - an antifungal medication. The search for antifungal agents with ...
2,1,3-Benzothiadiazole has been of interest as a redox-active organic component in flow batteries owing to its favourable solubility, low reduction potential and fast electrochemical kinetics. [ 15 ] Such properties in derivatives containing this heterocycle have made it of growing interest in dyestuffs , [ 16 ] white light-emitting polymers ...
Benzothiazole, or more specifically 1,3-benzothiazole, is an aromatic heterocyclic compound with the chemical formula C 7 H 5 NS.It is colorless, slightly viscous liquid. Although the parent compound, benzothiazole is not widely used, many of its derivatives are found in commercial products or in
The molecular formula C 6 H 4 N 2 S may refer to: 1,2,3-Benzothiadiazole , a benzene ring that is fused to a 1,2,3-thiadiazole 2,1,3-Benzothiadiazole , a benzene ring that is fused to a 1,2,5-thiadiazole
The first synthesis of the parent 1,2,3-benzothiadiazole-7-carboxylic acid was disclosed in patents filed by Ciba-Geigy. [7] The heterocyclic ring of the 1,2,3-benzothiadiazole core is formed by the classic ring-closure of a thiol onto a diazonium group adjacent in its benzene ring. [ 11 ]