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Asymptomatic elevation of serum liver enzyme concentrations occurs in 10% to 20% of people taking INH, and liver enzyme concentrations usually return to normal even when treatment is continued. [36] Isoniazid has a boxed warning for severe and sometimes fatal hepatitis, which is age-dependent at a rate of 0.3% in people 21 to 35 years old and ...
Please refer to the entry on isoniazid for details on other neurological side effects of INH. [citation needed] Rashes are most frequently due to PZA, but can occur with any of the TB drugs. Test dosing using the same regimen as detailed below for hepatitis may be necessary to determine which drug is responsible.
It combines isoniazid, pyridoxine, sulfamethoxazole, and trimethoprim. [1] Specifically it is used to prevent tuberculosis, toxoplasmosis, pneumonia, malaria, and isosporiasis. [2] It is taken by mouth. [1] Side effects may include trouble concentrating, numbness, vomiting, and rash. [2] Serious side effects may include liver problems. [2]
It is a fixed dose combination of ethambutol and isoniazid. [1] It is used along with other antituberculosis medication. [1] It is taken by mouth. [1] Side effects are those of the underlying medications. [1] More common side effects include poor coordination, numbness, and liver problems. [2]
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis. [1] It is a fixed dose combination of isoniazid and rifampicin (rifampin). [1] It is used together with other antituberculosis medication. [1] It is taken by mouth. [1] It is on the World Health Organization's List of Essential Medicines. [2]
It is a fixed dose combination of ethambutol, isoniazid, pyrazinamide, and rifampicin. [1] It is used either alone or with other antituberculosis medication. [1] It is taken by mouth. [1] Side effects are those of the underlying medications. [1] Pyridoxine may be used to decrease the risk of numbness. [2]
It is used either by itself or along with other antituberculosis medication. [1] It is taken by mouth. [1] Side effects are those of the underlying medications. [1] These may include poor coordination, loss of appetite, nausea, joint pain, feeling tired, and numbness. [2] Severe side effects include liver problems. [3]
In active tuberculosis it is used together with other antituberculosis medications. [2] In latent tuberculosis it is typically used with isoniazid. [2] It is taken by mouth. [2] Common side effects include low neutrophil counts in the blood, elevated liver enzymes, and white blood cells in the urine. [3]