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Metoprolol, sold under the brand name Lopressor among others, is a medication used to treat angina, high blood pressure and a number of conditions involving an abnormally fast heart rate. [4] It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines . [ 4 ]
The progress in β-blocker development led to the introduction of drugs with variety of properties. β-blockers were developed having a relative selectivity for cardiac β1-receptors (for example metoprolol and atenolol), partial adrenergic agonist activity , concomitant α-adrenergic blocking activity (for example labetalol and carvedilol) and ...
Atenolol is a beta blocker medication primarily used to treat high blood pressure and heart-associated chest pain. [7] Although used to treat high blood pressure, it does not seem to improve mortality in those with the condition. [8] [9] Other uses include the prevention of migraines and treatment of certain irregular heart beats.
Atenolol: Selective beta-1 blocker: Hypertension, angina and acute myocardial infarction [38] ALONET [39] Metoprolol: Selective beta-1 blocker: Angina, heart failure, myocardial infarction, atrial fibrillation and hypertension [40] BETALOC [41] Butaxamine: Selective beta-2 blocker: Not used clinically, use in animal and tissue experiments [42 ...
For the treatment of primary hypertension (high blood pressure), meta-analyses of studies which mostly used atenolol have shown that although beta blockers are more effective than placebo in preventing stroke and total cardiovascular events, they are not as effective as diuretics, medications inhibiting the renin–angiotensin system (e.g., ACE ...
153 11554 Ensembl ENSG00000043591 ENSMUSG00000035283 UniProt P08588 P34971 RefSeq (mRNA) NM_000684 NM_007419 RefSeq (protein) NP_000675 NP_031445 Location (UCSC) Chr 10: 114.04 – 114.05 Mb Chr 19: 56.71 – 56.72 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The beta-1 adrenergic receptor (β 1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene ...
Visual definition of an antagonist, where it compared to agonists and reverse agonists. An adrenergic antagonist is a drug that inhibits the function of adrenergic receptors.
Atenolol is a type of sympatholytic drug. Atenolol is a selective β1 antagonist that is clinically used to treat hypertension, angina and cardiac dysrhythmias. [14] Since atenolol is selective to β1 receptor, it only acts on β1 receptors which are located in the heart. [15]