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De Quervain syndrome occurs when two tendons that control movement of the thumb become constricted by their tendon sheath in the wrist. [3] [5] [6] This results in pain and tenderness on the thumb side of the wrist. [3] Radial abduction of the thumb is painful. [6] On some occasions, there is uneven movement or triggering of the thumb with ...
Diagnosis is typically based on symptoms and signs after excluding other possible causes. [2] Trigger digits can resolve without treatment. Treatment options that are disease modifying include steroid injections and surgery. [3] Splinting immobilization of the finger may or may not be disease modifying.
Two eponymous diseases are named after Quervain: De Quervain's thyroiditis: Subacute, non-bacterial inflammation of the thyroid gland, often after viral infection of respiratory tract. De Quervain's disease: inflammation of the sheath or tunnel that surrounds two tendons that control movement of the thumb. Sometimes called "washer woman's sprain".
Adverse effects include a transient increase in serum glucose level, and poor wound healing (controversial). Medications include dexamethasone. Butyrophenones are typically administered as a single injection at the end of surgery. Adverse effects include prolongation of the QT interval on EKG. Medications include droperidol and haloperidol.
Headache — an often transient side effect that is common to most serotonin reuptake inhibitors and that most often occurs at the beginning of therapy or after a dose escalation. Nausea — an adverse effect that is more common with venlafaxine than with the SSRIs. Usually transient and less severe in those receiving the extended release ...
Particular medications can result in MRONJ, a serious but uncommon side effect in certain individuals. Such medications are frequently used to treat diseases that cause bone resorption such as osteoporosis, or to treat cancer. The main groups of drugs involved are anti-resorptive drugs, and anti-angiogenic drugs.
An example of such adjuvant therapy is the additional treatment [1] usually given after surgery where all detectable disease has been removed, but where there remains a statistical risk of relapse due to the presence of undetected disease. If known disease is left behind following surgery, then further treatment is not technically adjuvant.
De Quervain's thyroiditis, also known as subacute granulomatous thyroiditis or giant cell thyroiditis, is a self-limiting inflammatory illness of the thyroid gland. [1] De Quervain thyroiditis is characterized by fever , flu-like symptoms , a painful goiter , and neck pain .