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Complex regional pain syndrome is uncommon, and its cause is not clearly understood. CRPS typically develops after an injury, surgery, heart attack, or stroke. [8] [12] Investigators estimate that 2–5% of those with peripheral nerve injury, [13] and 13–70% of those with hemiplegia (paralysis of one side of the body) [14] will develop
This form, similarly to other forms of AMPS, is known to be able to spread from one limb to a new limb. 35% of people effected with CRPS report full-body impacts from the condition. Common symptoms of CRPS include musculoskeletal pain; swelling; changes to the skin texture, color, or temperature; and limited range of motion. [11]
Chronic pain continues past normal healing times and therefore does not have the same function as acute pain, which is to signal that there is a threat so the body can avoid future danger. [ 3 ] [ 4 ] Chronic pain is considered a syndrome because of the associated symptoms that develop in those experiencing this disorder. [ 5 ]
Allodynia is a clinical feature of many painful conditions, such as neuropathies, [4] complex regional pain syndrome, postherpetic neuralgia, fibromyalgia, and migraine. Allodynia may also be caused by some populations of stem cells used to treat nerve damage including spinal cord injury .
The process known as "molecular mimicry" occurs when an infectious organism that shares epitopes from its host's afflicted tissue triggers an immune response in the host. However, only a small number of convincingly identified specific targets for such a response have been found in chronic inflammatory demyelinating polyneuropathy.
According to Kukushkin, the memories stored in non-brain cells in other parts of the body are memories strictly related to the roles that those specific cells play in human health. Thus, he detailed:
Complex regional pain syndrome (CRPS), a disorder of a portion of the body which manifests as extreme pain and other symptoms Topics referred to by the same term This disambiguation page lists articles associated with the title CPRS .
It states, "Complex regional pain syndrome (CRPS), formerly reflex sympathetic dystrophy (RSD) or "causalgia",…" Thie "or" part is misleading in the extreme--it implies that RSD and causalgia are two names for the same thing.