Search results
Results from the WOW.Com Content Network
Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. [1] [2] The term neurosteroid was coined by the French physiologist Étienne-Émile Baulieu and refers to steroids synthesized in ...
Erminio "Mimo" Costa (March 9, 1924 – November 28, 2009) was an Italian-American neuroscientist. [3] His research interests covered brain serotonergic activity in health and disease, benzodiazepine-GABA interactions, [4] benzodiazepine action at GABAA receptors, neurophysiological role of neurosteroids, [5] and GABAergic dysfunction and changes in the expression of reelin and GAD67 in ...
This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors. It includes inhibitory , excitatory , and neurotrophic neurosteroids as well as pheromones and vomeropherines .
One in four U.S. adults suspects they may have ADHD and drugs are a first line of treatment for this condition. But what does research say about their impact on the brain and quality of life?
UCHealth Medical Center of the Rockies, located in Loveland, Colorado, is the sister hospital of Poudre Valley Hospital in Fort Collins, Colorado.
A neurosteroidogenesis inhibitor is a drug that inhibits the production of endogenous neurosteroids.Neurosteroids include the excitatory neurosteroids pregnenolone sulfate, dehydroepiandrosterone (DHEA), and dehydroepiandrosterone sulfate (DHEA-S), and the inhibitory neurosteroids allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol, among others. [1]
The brain requires the use of many neurosteroids to develop and function properly. These molecules are often identified as one of many common substances including thyroid hormones, glucocorticoids, and sex hormones. However in recent studies, throughout the brain and spinal fluid, vitamin D has begun to surface as one of these neurosteroids.
Pherines specifically target nasal chemosensory cells [5] [6] and mediate selective modulation of brain areas like the limbic amygdala, hypothalamus, hippocampus, and prefrontal cortex. [7] In clinical trials, pherines formulated for intranasal administration in ultra low doses (nanogram to low microgram quantities) showed rapid onset of ...