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Metreleptin, sold under the brand name Myalept among others, is a synthetic analog of the hormone leptin used to treat various forms of dyslipidemia.It has been approved in Japan for metabolic disorders including lipodystrophy and in the United States as replacement therapy to treat the complications of leptin deficiency, in addition to diet, in patients with congenital generalized or acquired ...
Behavior therapy for depression is sometimes referred to as behavioral activation. [26] In addition, behavioral activation appears to take less time and lead to longer lasting change. [27] Two well-researched treatment manuals include Social skills training for depression [28] and Behavioral activation treatment for depression. [29]
Electroconvulsive therapy is generally only considered as a treatment option in severe cases of treatment-resistant depression. It is used when medication has repeatedly failed to improve symptoms, and usually when the patient's symptoms are so severe that they have been hospitalized.
In 1927, Sakel, who had recently qualified as a medical doctor in Vienna and was working in a psychiatric clinic in Berlin, began to use low (sub-coma) doses of insulin to treat drug addicts and psychopaths, and when one of the patients experienced improved mental clarity after having slipped into an accidental coma, Sakel reasoned the treatment might work for mentally ill patients. [3]
The term "shock therapy" [3] gained widespread attention following Sakel's 1933 publication on the efficacy of insulin therapy in schizophrenia treatment. This method, revolutionary at the time for addressing psychosis, entailed insulin injections to induce convulsions and comas.
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