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In the sympathetic division, neurons are mostly adrenergic (that is, epinephrine and norepinephrine function as the primary neurotransmitters). Notable exceptions to this rule include the sympathetic innervation of sweat glands and arrectores pilorum muscles where the neurotransmitter at both pre and post ganglionic synapses is acetylcholine.
A preganglionic fibre may synapse to 15–20 postganglionic fibres. The postganglionic neurons extend across most of the body. [4] Upon exiting the sympathetic chain, the fibres enter a less-myelinated gray ramus communicans. There is still a myelin sheath present – but in far lower amounts compared to the white ramus communicans.
There are two kinds of neurons involved in the transmission of any signal through the sympathetic system: pre-ganglionic and post-ganglionic. The shorter preganglionic neurons originate in the thoracolumbar division of the spinal cord specifically at T1 to L2~L3, and travel to a ganglion, often one of the paravertebral ganglia, where they synapse with a postganglionic neuron.
From here, the postganglionic sympathetic neuron can travel back out the grey ramus communicans of that level to the mixed spinal nerve and onto the effector organ. The preganglionic neuron can travel superiorly or inferiorly to a sympathetic paravertebral ganglion of a higher or lower level where it can synapse with a postganglionic ...
Electrical impulses carried by the sympathetic nervous system are converted to a chemical response in the adrenal gland. Chromaffin cells contained in the adrenal medulla act as postganglionic nerve fibers that release this chemical response into the blood as a circulating messenger. The sympathoadrenal system can activate and discharge ...
Small intensely fluorescent cells (SIF cells) are the interneurons of the sympathetic ganglia (postganglionic neurons) of the Sympathetic division of the autonomic nervous system (ANS). The neurotransmitter for these cells is dopamine. They are a neural crest derivative and share a common sympathoadrenal precursor cell with sympathetic neurons ...
Sudomotor function refers to the autonomic nervous system control of sweat gland activity in response to various environmental and individual factors. Sweat production is a vital thermoregulatory mechanism used by the body to prevent heat-related illness as the evaporation of sweat is the body’s most effective method of heat reduction and the only cooling method available when the air ...
Recordings from efferent postganglionic sympathetic C fibers of the muscles and skin yield insights into the neural control of autonomic effector organs like blood vessels and sweat glands. [16] Readings of afferent discharges from C nociceptors identified by marking method have also proved helpful in revealing the mechanisms underlying ...