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List of drugs used to treat schistosomiasis. 1 language. ... "Current chemotherapy arsenal for schistosomiasis mansoni: alternatives and challenges".
While chemotherapeutic drugs, such as praziquantel, oxamniquine and metrifonate both no longer on the market, are currently considered safe and effective for the treatment of schistosomiasis, reinfection occurs frequently following drug treatment, thus a vaccine is sought to provide long-term treatment.
Main article: Human parasite Endoparasites Protozoan organisms Common name of organism or disease Latin name (sorted) Body parts affected Diagnostic specimen Prevalence Source/Transmission (Reservoir/Vector) Granulomatous amoebic encephalitis and Acanthamoeba keratitis (eye infection) Acanthamoeba spp. eye, brain, skin culture worldwide contact lenses cleaned with contaminated tap water ...
Thus, it should be administered 6 to 8 weeks after suspected infection (contact with infested freshwater). There has been limited evidence on possible drug resistance among the schistosomes due to reports of low cure rates. Oxaminiquine is another treatment for schistosomiasis, but it is not widely available, nor is it routinely used. [5]
Post-treatment monitoring Osteopontin (OPN) is a promising tool for monitoring praziquantel efficacy and post-treatment fibrosis regression as (OPN) expression is modulated by S. mansoni egg antigens and its levels correlate with the severity of schistosomiasis fibrosis and portal hypertension in mice and humans. Praziquantel pharmacotherapy ...
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Anthiomaline was the drug of choice, but this leads to relapse of the symptoms after two months of the treatment. [3] Praziquantel proved better than any other drug. Recently, Dr. M. C. Agrawal has successfully treated cases of nasal schistosomiasis by administering triclabendazole.
Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms , such as heartworm and intestinal worms, in dogs, cats, horses, cattle, sheep and wombats. [4] Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels .
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