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Drug tolerance is indicative of drug use but is not necessarily associated with drug dependence or addiction. [4] The process of tolerance development is reversible (e.g., through a drug holiday [5]) and can involve both physiological factors and psychological factors. [6] One may also develop drug tolerance to side effects, [7] in which case ...
Tachyphylaxis (Greek ταχύς, tachys, "rapid", and φύλαξις, phylaxis, "protection") is a medical term describing an acute, sudden decrease in response to a drug after its administration (i.e., a rapid and short-term onset of drug tolerance). [1] It can occur after an initial dose or after a series of small doses.
The Texas Department of Licensing and Regulation (TDLR) is a state agency of Texas. TDLR is responsible for licensing and regulating a broad range of occupations, businesses, facilities, and equipment in Texas. [1] TDLR has its headquarters in the Ernest O. Thompson State Office Building in Downtown Austin. [2] [3]
Benzodiazepine dependence develops with long-term use, even at low therapeutic doses, [2] often without the described drug seeking behavior and tolerance. [3] [4] Addiction consists of people misusing or craving the drug, not to relieve withdrawal symptoms, but to experience its euphoric or intoxicating effects.
Reverse tolerance or drug sensitization is a pharmacological phenomenon describing subjects' increased reaction (positive or negative) to a drug following its repeated use. [4] Not all drugs are subject to reverse tolerance. This is the opposite of drug tolerance, in which the effect or the subject's reaction decreases following its repeated ...
Tolerability, however, is often relative to the severity of the medical condition a drug is designed to treat. [1] For instance, cancer patients may tolerate significant pain or discomfort during a chemotherapeutic study with the hope of prolonging survival or finding a cure, whereas patients experiencing a benign condition, such as a headache ...
Princess Kate Middleton is offering an encouraging message to those battling substance abuse issues in honor of Addiction Awareness Week. “As Patron of the Forward Trust, I am delighted to, once ...
Research has shown, when drug use begins at an early age, there is a greater possibility for addiction to occur. [14] Three exacerbating factors that can influence substance use to become substance use are social approval, lack of perceived risks, and availability of drugs in the community. Youths from certain demographics are also at higher ...
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