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The difference with plasma donation is that the blood goes through a machine that collects only the plasma and sends the red and white blood cells and platelets back to the donor in a saline solution.
Donating plasma is similar in many ways to whole blood donation, though the end product is used for different purposes. Most plasmapheresis is for fractionation into other products; other blood donations are transfused with relatively minor modifications. Plasma that is collected solely for further manufacturing is called Source Plasma.
When donating whole blood or packed red blood cell (PRBC) transfusions, O-is the most desirable and is considered a "universal donor," since it has neither A nor B antigens and can be safely transfused to most recipients. Type AB+ is the "universal recipient" type for PRBC donations. However, for plasma the situation is somewhat reversed.
The reason that donating plasma takes so long is because of the process of separating the plasma from the blood at the time of the donation. There is nothing that you have to do except sit there ...
Usually the component returned is the red blood cells, the portion of the blood that takes the longest to replace. Using this method an individual can donate plasma or platelets much more frequently than they can safely donate whole blood. [76] These can be combined, with a donor giving both plasma and platelets in the same donation. [citation ...
Selling plasma is becoming a common way to get a bit of extra cash on the side. Depending on qualifications and health, plasma donors can $360 to $1,000 monthly for donations.
In addition, some (though not all) centers defer further platelet donations until the red blood cells can be replenished. In most cases, blood plasma is returned to the donor as well. However, in locations that have plasma processing facilities, a part of the donor's plasma can also be collected in a separate blood bag (see plasmapheresis).
1) Plasma exchange is not synonymous with plasmapheresis. As it is implied in the article this procedure can be used for donation of plasma therefore nothing is exchanged also it can be used for removal of the plasma and replacing it with other fluids, usually Normal Saline or Albumin rather than Plasma. This latter process is called Plasma ...
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