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People suffered from "chronic or recurrent fatigue", among a large number of other symptoms. [1]: 28–29 The initial link between elevated antibodies and the Epstein–Barr virus led to the name "chronic Epstein–Barr virus syndrome". The CDC renamed it chronic fatigue syndrome (CFS), as a viral cause could not be confirmed in studies.
While fatigue is often prominent, it is "more than fatigue following a stressor". [6] Other symptoms that may occur during PEM include cognitive impairment, flu-like symptoms, pain, weakness, and trouble sleeping. [6] [4] Though typically cast as a worsening of existing symptoms, patients may experience some symptoms exclusively during PEM. [6]
The fatigue must have lasted for 6 months or longer, and be present at least 50% of the time; Other symptoms are possible, such as muscle pain, mood problems, or sleep disturbance; Conditions known to cause severe fatigue and some mental conditions exclude a diagnosis. Post-infectious fatigue syndrome also requires evidence of a prior infection ...
Chronic fatigue is characterized by at least six months of severe exhaustion not helped by bed rest. Patients also report pain, brain fog and other symptoms that can get worse after exercise, work ...
PAIS symptoms are often non-specific and similar despite diverse prior infections. Symptoms commonly included in definitions of PAIS include post-exertional malaise, severe fatigue, neurocognitive and sensory symptoms, flu-like symptoms, unrefreshing sleep, muscle pain, and joint pain. Symptoms can vary among affected people. [1]
Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [1]: 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise. Clinical ...
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