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The cells of the olfactory epithelium, including olfactory sensory neurons, begin to differentiate soon after the induction of the olfactory placode. Once the olfactory sensory neurons differentiate, they express odorant receptors, which transduce odorant information from the environment to the central nervous system and aids in the development ...
The ORNs are located in the olfactory epithelium in the nasal cavity. The cell bodies of the ORNs are distributed among all three of the stratified layers of the olfactory epithelium. [4] Many tiny hair-like non-motile cilia protrude from the olfactory receptor cell's dendrites. The dendrites extend to the olfactory epithelial surface and each ...
The olfactory epithelium is made up of at least six morphologically and biochemically different cell types. [20] The proportion of olfactory epithelium compared to respiratory epithelium (not innervated, or supplied with nerves) gives an indication of the animal's olfactory sensitivity. Humans have about 10 cm 2 (1.6 sq in) of olfactory ...
The olfactory mucosa is the neuroepithelial mucosa [1] lining the roof and upper parts of the septum and lateral wall of the nasal cavity [1] [2] which contains bipolar neurons of the primary receptor neurons of the olfactory pathway, as well as supporting cells.
The main olfactory bulb transmits pulses to both mitral and tufted cells, which help determine odor concentration based on the time certain neuron clusters fire (called 'timing code'). These cells also note differences between highly similar odors and use that data to aid in later recognition.
In vertebrates, the olfactory receptors are located in both the cilia and synapses of the olfactory sensory neurons [5] and in the epithelium of the human airway. [6] Sperm cells also express odor receptors, which are thought to be involved in chemotaxis to find the egg cell.
Olfactory glands, also known as Bowman's glands, are a type of nasal gland situated in the part of the olfactory mucosa beneath the olfactory epithelium, that is the lamina propria, a connective tissue also containing fibroblasts, blood vessels and bundles of fine axons from the olfactory neurons.
The olfactory bulb is supported and protected by the cribriform plate of the ethmoid bone, which in mammals separates it from the olfactory epithelium, and which is perforated by olfactory nerve axons. The bulb is divided into two distinct structures: the main olfactory bulb and the accessory olfactory bulb.