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Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men. [13] It is also being studied for other types of cancer. [13] It has been used for Albright syndrome. [14] Tamoxifen is typically taken daily by mouth for five years for breast cancer. [14]
Combined hormonal contraception (CHC), or combined birth control, is a form of hormonal contraception which combines both an estrogen and a progestogen in varying formulations. [ 1 ] [ 2 ] The different types available include the pill , the patch and the vaginal ring , which are all widely available, [ 3 ] and an injection , which is available ...
Tamoxifen is a pure antiestrogenic trans-isomer and has differential actions at estrogen target tissues throughout the body. Tamoxifen is selectively antiestrogenic in the breast but estrogen-like in bones and endometrial cancer. [24] Tamoxifen undergo phase I metabolism in the liver by microsomal cytochrome P450 (CYP) enzymes.
Hormonal contraception works primarily by preventing ovulation, but it may also thicken the cervical mucus inhibiting sperm penetration. [ 3 ] [ 4 ] [ 5 ] Hormonal contraceptives also have effects on the endometrium, [ 6 ] [ 7 ] that theoretically could affect implantation.
Hormonal contraception refers to birth control methods that act on the endocrine system. Almost all methods are composed of steroid hormones , although in India one selective estrogen receptor modulator is marketed as a contraceptive.
The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women. It is the oral form of combined hormonal contraception .
Estrogens have contraceptive effects and are used in combination with progestins (synthetic progestogens) in birth control to prevent pregnancy in women. This is referred to as combined hormonal contraception. The contraceptive effects of estrogens are mediated by their antigonadotropic effects and hence by inhibition of ovulation.
Birth control, also known as contraception, anticonception, and fertility control, is the use of methods or devices to prevent pregnancy. [1] Birth control has been used since ancient times, but effective and safe methods of birth control only became available in the 20th century. [2]
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