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The accessory olfactory bulb resides on the dorsal-posterior region of the main olfactory bulb and forms a parallel pathway. Destruction of the olfactory bulb results in ipsilateral anosmia, while irritative lesions of the uncus can result in olfactory and gustatory hallucinations. Flow of olfactory information from receptors to glomeruli layer
All glomeruli are located near the surface of the olfactory bulb. The olfactory bulb also includes a portion of the anterior olfactory nucleus, the cells of which contribute fibers to the olfactory tract. [4] They are the initial sites for synaptic processing of odor information coming from the nose.
Human Olfactory bulbs and Olfactory tracts outlined in red. The olfactory system is a vital sense, and its dysfunction may lead to a reduced quality of life, an inability to determine hazardous odors, decreased pleasure in eating, and poor mental health. [32]
The anterior olfactory nucleus (AON) also called the anterior olfactory cortex, is a portion of the vertebrate forebrain. It is involved in the sense of smell (olfaction), and has influence on other olfactory areas including the olfactory bulb and the piriform cortex. [1] [2] The AON is one of the major secondary structures of olfaction. [3]
The Lady and the Unicorn, a Flemish tapestry depicting the sense of smell, 1484–1500. Musée national du Moyen Âge, Paris.. Early scientific study of the sense of smell includes the extensive doctoral dissertation of Eleanor Gamble, published in 1898, which compared olfactory to other stimulus modalities, and implied that smell had a lower intensity discrimination.
The olfactory epithelium contains olfactory sensory neurons, whose axons innervate the olfactory bulb. In order for olfactory sensory neurons to function properly, they must express odorant receptors and the proper transduction proteins on non-motile cilia that extend from the dendritic knob in addition to projecting their axons to the ...
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