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  2. L-DOPA - Wikipedia

    en.wikipedia.org/wiki/L-DOPA

    l-DOPA, also known as l-3,4-dihydroxyphenylalanine and used medically as levodopa, is made and used as part of the normal biology of some plants [2] and animals, including humans. Humans, as well as a portion of the other animals that utilize l -DOPA, make it via biosynthesis from the amino acid l -tyrosine .

  3. Levodopa - Wikipedia

    en.wikipedia.org/wiki/Levodopa

    Once levodopa has entered the central nervous system, it is converted into dopamine by the enzyme aromatic l-amino acid decarboxylase (AAAD), also known as DOPA decarboxylase (DDC). Pyridoxal phosphate (vitamin B 6) is a required cofactor in this reaction, and may occasionally be administered along with levodopa, usually in the form of pyridoxine.

  4. Tyrosine hydroxylase - Wikipedia

    en.wikipedia.org/wiki/Tyrosine_hydroxylase

    Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). [5] [6] It does so using molecular oxygen (O 2), as well as iron (Fe 2+) and tetrahydrobiopterin as cofactors.

  5. Aromatic L-amino acid decarboxylase - Wikipedia

    en.wikipedia.org/wiki/Aromatic_L-amino_acid_de...

    Aromatic L-amino acid decarboxylase (AADC or AAAD), also known as DOPA decarboxylase (DDC), tryptophan decarboxylase, and 5-hydroxytryptophan decarboxylase, is a lyase enzyme (EC 4.1.1.28), located in region 7p12.2-p12.1.

  6. Dopamine agonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_agonist

    The third stage is the formation of dopamine by removing the carboxylic acid group from L-DOPA, catalysed by the enzyme dopa decarboxylase. [ 31 ] Levodopa is also too polar to cross the blood brain barrier but it is an amino acid and has a specialized transporter called L-type amino acid transporter or LAT-1 that helps it diffuse through the ...

  7. File:3,4-Dihydroxy-L-phenylalanin (Levodopa).svg - Wikipedia

    en.wikipedia.org/wiki/File:3,4-Dihydroxy-L...

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  8. 3-O-Methyldopa - Wikipedia

    en.wikipedia.org/wiki/3-O-methyldopa

    3-O-methyldopa is a major metabolite of L-3,4-dihydroxyphenylalanine (L-DOPA) and is formed by catechol-O-methyltransferase (COMT). One of the L-DOPA's metabolic pathways is the decarboxylation and the other is the O-methylation. L-DOPA has the main role in

  9. C9H11NO4 - Wikipedia

    en.wikipedia.org/wiki/C9H11NO4

    L-DOPA (or levodopa) Index of chemical compounds with the same molecular formula This set index page lists chemical structure articles associated with the same molecular formula .

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