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For Seasonal Affective Disorder (SAD), a randomized controlled trial (RCT) comparing high (4.5x10 14 ions/second) and low (1.7x10 11 ions/second) flow rate negative air ionization with bright light therapy found that the post-treatment improvement percentage was 57.1% for bright light, 47.9% for high-density ions and 22.7% for low-density ions. [8]
Negative air ions (NAI) are important air component, generally referring to the collections of negatively charged single gas molecules or ion clusters in the air. They play an essential role in maintaining the charge balance of the atmosphere. [1] [2] The main components of air are molecular nitrogen and oxygen.
An air ioniser (or negative ion generator or Chizhevsky's chandelier) is a device that uses high voltage to ionise (electrically charge) air molecules. Negative ions, or anions , are particles with one or more extra electrons , conferring a net negative charge to the particle.
At high altitude, in the short term, the lack of oxygen is sensed by the carotid bodies, which causes an increase in the breathing depth and rate . However, hyperpnea also causes the adverse effect of respiratory alkalosis , inhibiting the respiratory center from enhancing the respiratory rate as much as would be required.
Humans can smell chlorine gas at ranges from 0.1–0.3 ppm. According to a review from 2010: "At 1–3 ppm, there is mild mucous membrane irritation that can usually be tolerated for about an hour. At 5–15 ppm, there is moderate mucous membrane irritation. At 30 ppm and beyond, there is immediate chest pain, shortness of breath, and cough.
Oxygen toxicity is a condition resulting from the harmful effects of breathing molecular oxygen (O 2) at increased partial pressures.Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lungs, and eyes.
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Hypoventilation is not synonymous with respiratory arrest, in which breathing ceases entirely and death occurs within minutes due to hypoxia and leads rapidly into complete anoxia, although both are medical emergencies. Hypoventilation can be considered a precursor to hypoxia and its lethality is attributed to hypoxia with carbon dioxide toxicity.