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An ulcer is a sore on the skin or a mucous membrane, accompanied by the disintegration of tissue. Ulcers can result in complete loss of the epidermis and often portions of the dermis and even subcutaneous fat. Ulcers are most common on the skin of the lower extremities and in the gastrointestinal tract. An ulcer that appears on the skin is ...
Bleeding ulcers may be treated by endoscopy, with open surgery typically only used in cases in which it is not successful. [2] Peptic ulcers are present in around 4% of the population. [1] New ulcers were found in around 87.4 million people worldwide during 2015. [5] About 10% of people develop a peptic ulcer at some point in their life. [9]
In Canada, between 1998 and 2000, the number of new cases per year was 12.9 per 100,000 population or 4,500 new cases. The number of people affected was estimated to be 211 per 100,000 or 104,000. [187]
Basal-cell carcinoma (BCC), also known as basal-cell cancer, basalioma [7] or rodent ulcer, [8] is the most common type of skin cancer. [2] It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it . [ 1 ]
The drug Elmiron helps, for some patients, to prevent the formation of Hunner's ulcers by coating the bladder wall, thus making it harder for the acid in urine to irritate the bladder wall lining, which can lead to ulceration. Elmiron is a controversial medication within the interstitial cystitis community, with its efficacy questioned by many.
Classically, there is a solitary ulcer. But only 20% of patients have a single ulcer whereas in other cases there may be multiple lesions. [6] The size of the ulcers is usually 0.5–4 cm. [5] The lesion is most often located on the anterior (front) or lateral (side) rectal wall, centered on a rectal fold, [1] usually 10 cm from the anal verge. [8]
[31] [32] Pressure ulcers are caused by ischemia that occurs when pressure on the tissue is greater than the pressure in capillaries, and thus restricts blood flow into the area. [30] Muscle tissue, which needs more oxygen and nutrients than skin does, shows the worst effects from prolonged pressure. [ 32 ]
Callous ulcer is a chronic nonhealing ulcer with hard indurated base and inelastic margins. [1] It usually contains unhealthy pale granulation tissue . It may last for months to years and does not show any tendency to heal.