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Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and ...
InterPro. The steroidogenic acute regulatory protein, commonly referred to as StAR (STARD1), is a transport protein that regulates cholesterol transfer within the mitochondria, which is the rate-limiting step in the production of steroid hormones. It is primarily present in steroid-producing cells, including theca cells and luteal cells in the ...
301 16952 Ensembl ENSG00000135046 ENSMUSG00000024659 UniProt P04083 Q5T3N0 P10107 RefSeq (mRNA) NM_000700 NM_010730 RefSeq (protein) NP_000691 NP_034860 Location (UCSC) Chr 9: 73.15 – 73.17 Mb Chr 19: 20.35 – 20.37 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Annexin A1, also known as lipocortin I, is a protein that is encoded by the ANXA1 gene in humans. Function Annexin A1 ...
Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and autoimmune conditions [14] such as asthma, [15] uveitis, pyoderma gangrenosum, rheumatoid arthritis, urticaria, [16] angioedema, [16] ulcerative colitis, pericarditis, temporal arteritis and Crohn's disease, Bell's ...
Steroid hormone receptor. Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells. They are generally intracellular receptors (typically cytoplasmic or nuclear) and initiate signal transduction for steroid hormones which lead to changes in gene expression over a time period of hours to days.
Drostanolone propionate, or dromostanolone propionate, sold under the brand names Drolban, Masteril, and Masteron among others, is an androgen and anabolic steroid (AAS) medication which was used to treat breast cancer in women but is now no longer marketed. [1][2] It is given by injection into muscle. [1]
The objective of cancer screening is to detect cancer before symptoms appear, involving various methods such as blood tests, urine tests, DNA tests, and medical imaging. [1][2] The purpose of screening is early cancer detection, to make the cancer easier to treat and extending life expectancy. [3] In 2019, cancer was the second leading cause of ...
Cancer immunology is an interdisciplinary branch of biology concerned with the role of the immune system in the progression and development of cancer; the most well known application is cancer immunotherapy, where the immune system is used to treat cancer. [1][2] Cancer immunosurveillance is a theory formulated in 1957 by Burnet and Thomas, who ...