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The bromelain gel is contraindicated in persons allergic to pineapple or the enzyme papain. [3] The most common side-effects are fever (19% of patients in studies) and local pain (3.6%). Wound infections occur no more frequently than under standard treatment. [3]
Bromantane is well tolerated and elicits few side effects (including peripheral sympathomimetic effects and hyperstimulation), does not appear to produce tolerance or dependence, has not been associated with withdrawal symptoms upon discontinuation, and displays an absence of addiction potential, contrary to typical stimulants.
Identifying a direct cause for insomnia, particularly in cases of primary insomnia, can be challenging. However, various issues can contribute. Here are some of the most common causes and risk ...
The usage of melatonin as a treatment for insomnia in adults has increased from 0.4% between 1999 and 2000 to nearly 2.1% between 2017 and 2018. [164] While the use of melatonin in the short-term has been proven to be generally safe and is shown to not be a dependent medication, side effects can still occur. [165]
Bromazepam, sold under many brand names, is a benzodiazepine.It is mainly an anti-anxiety agent with similar side effects to diazepam.In addition to being used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery.
Psychophysiological insomnia is anxiety-induced. Idiopathic insomnia generally begins in childhood and lasts for the rest of a person's life. It's suggested that idiopathic insomnia is a neurochemical problem in a part of the brain that controls the sleep-wake cycle, resulting in either under-active sleep signals or over-active wake signals.
There has also been research into the utility of the individual components of CBT-I, when delivered as monotherapies or multi-component therapies without cognitive therapy. A 2023 systematic review [39] demonstrated that just stimulus control and sleep restriction are effective treatment options for insomnia in older adults. It also indicated ...
Insomnia disorder (primary insomnia), chronic difficulty in falling asleep or maintaining sleep when no other cause is found for these symptoms. Insomnia can also be comorbid with or secondary to other disorders. Kleine–Levin syndrome, a rare disorder characterized by persistent episodic hypersomnia and cognitive or mood changes. [84]