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Misoprostol is a synthetic prostaglandin medication used to prevent and treat stomach and duodenal ulcers, induce labor, cause an abortion, and treat postpartum bleeding due to poor contraction of the uterus. [10] [11] It is taken by mouth when used to prevent gastric ulcers in people taking nonsteroidal anti-inflammatory drugs (NSAID). [11]
Failure to take the misoprostol may result in any of these outcomes: the fetus may be terminated, but not fully expelled from the uterus (possibly accompanied by hemorrhaging) and may require surgical intervention to remove the fetus; or the pregnancy may be successfully aborted and expelled; or the pregnancy may continue with a healthy fetus.
Misoprostol causes the uterus to contract and empty. As a two-drug regimen, the medications successfully end a pregnancy nearly 100% of the time, according to a 2015 study published in the journal ...
Misoprostol can cause unpleasant side effects such as very high body temperatures and shivering. [28] Lower doses of misoprostol appear to be safer and cause less side effects. [28] Giving oxytocin in a solution of saline into the umbilical vein is a method of administering the drug directly to the placental bed and uterus. [29]
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Misoprostol has a variety of uses in obstetrics and gynecology. It is also used to relieve pain from duodenal ulcers when other treatments have been ineffective. [14] Misoprostol can be used to induce labor in patients at the end of pregnancy. It causes cervical ripening, or the thinning and shortening of the cervix in preparation for birth. It ...
Total abortion bans that consider humans to have full rights from the moment of conception have created a confusing legal domain that affects a wide range of areas, including assisted reproductive ...
The most common cause of spontaneous abortion during the first trimester is chromosomal abnormalities of the embryo or fetus, [46] [59] accounting for at least 50% of sampled early pregnancy losses. [60] Other causes include vascular disease (such as lupus), diabetes, other hormonal problems, infection, and abnormalities of the uterus. [59]