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  2. Peter Attia - Wikipedia

    en.wikipedia.org/wiki/Peter_Attia

    Peter Attia (born March 19, 1973) [1] is a Canadian-American author, physician, and researcher known for his work in longevity medicine. He is the author of Outlive: The Science and Art of Longevity .

  3. Outlive: The Science and Art of Longevity - Wikipedia

    en.wikipedia.org/wiki/Outlive:_The_Science_and...

    Outlive: The Science and Art of Longevity is a non-fiction health and wellness book authored by Peter Attia, a physician specializing in longevity, and co-written with journalist Bill Gifford. [1] Published in March 2023, Outlive was listed on The New York Times Best Seller list in 2023 and 2024.

  4. Sirolimus - Wikipedia

    en.wikipedia.org/wiki/Sirolimus

    Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).

  5. mTOR inhibitors - Wikipedia

    en.wikipedia.org/wiki/MTOR_inhibitors

    mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...

  6. mTOR - Wikipedia

    en.wikipedia.org/wiki/MTOR

    The mammalian target of rapamycin (mTOR), [5] also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene. [6] [7] [8] mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein ...

  7. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.

  8. Childhood immunizations in the United States - Wikipedia

    en.wikipedia.org/wiki/Childhood_immunizations_in...

    This vaccine is given as a series of shots, the first dose is given at birth, the second between 1 and 2 months, and the third, and possibly fourth, between 6 and 18 months. Some side effects of this vaccination include: soreness at injection site (1 in 4 children) fever of 99.9 degrees Fahrenheit or higher (1 in 15 children) brief fainting spell

  9. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose.It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1]