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  2. Mitragyna speciosa - Wikipedia

    en.wikipedia.org/wiki/Mitragyna_speciosa

    This is an accepted version of this page This is the latest accepted revision, reviewed on 26 February 2025. Plant species, recreational drug (kratom) Mitragyna speciosa Conservation status Least Concern (IUCN 3.1) Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade: Asterids Order: Gentianales Family: Rubiaceae Genus: Mitragyna Species: M ...

  3. Mitragynine - Wikipedia

    en.wikipedia.org/wiki/Mitragynine

    Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an atypical opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.

  4. 7-Hydroxymitragynine - Wikipedia

    en.wikipedia.org/wiki/7-Hydroxymitragynine

    7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.

  5. Hepatotoxin - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxin

    A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver.. It can be a side-effect, but hepatotoxins are also found naturally, such as microcystins and pyrrolizidine alkaloids, or in laboratory environments, such as carbon tetrachloride, or far more pervasively in the form of ethanol (drinking alcohol).

  6. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.

  7. Heptavalent botulism antitoxin - Wikipedia

    en.wikipedia.org/wiki/Heptavalent_botulism_antitoxin

    The CDC began supplying doses to the SNS in 2007 under a now $427 million contract with the DHHS, according to a Cangene press release. In 2010, the CDC replaced the licensed bivalent botulinum antitoxin AB (BAT-AB) and the investigational monovalent botulinum antitoxin E (BAT-E) with BAT when the former two products indications expired. This ...

  8. OECD Guidelines for the Testing of Chemicals - Wikipedia

    en.wikipedia.org/wiki/OECD_Guidelines_for_the...

    Section 5: Other Test Guidelines; Guidelines are numbered with three digit numbers, the section number being the first number. Sometimes guidelines are suffixed with a letter. Guidelines are under constant review, with guidelines being periodically updated, new guidelines being adopted, and guidelines being withdrawn.

  9. Category:Hepatotoxins - Wikipedia

    en.wikipedia.org/wiki/Category:Hepatotoxins

    Drugs and other substances that have been associated with significant hepatotoxicity (liver damage). Subcategories. This category has the following 2 subcategories ...

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