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A neurotransmitter is a type of molecule that carries signals between neurons (nerve cells) at synapses in the nervous system The main article for this category is Neurotransmitters . Wikimedia Commons has media related to Neurotransmitters .
GABA is the major inhibitory neurotransmitter in the brain, and glutamate is the major excitatory neurotransmitter. [130] Neurons link at synapses to form neural pathways , neural circuits , and large elaborate network systems such as the salience network and the default mode network , and the activity between them is driven by the process of ...
By regulating extracellular neurotransmitter levels, astrocytes help maintain proper synaptic function. This bidirectional communication between astrocytes and neurons add complexity to brain signaling, with implications for brain function and neurological disorders. [10] [11]
Inside the brain, dopamine functions as a neurotransmitter and neuromodulator, and is controlled by a set of mechanisms common to all monoamine neurotransmitters. [22] After synthesis, dopamine is transported from the cytosol into secretory vesicles, including synaptic vesicles , small and large dense core vesicles by a solute carrier —a ...
Neurotransmitter receptor – membrane receptor that can be activated by a neurotransmitter. Interactions between neurotransmitters and neurotransmitter receptors can evoke a wide range of differing responses from the cell receiving the signal, including excitation, inhibition, and various types of modulation. Category:Receptors
Inside the brain norepinephrine functions as a neurotransmitter and neuromodulator, and is controlled by a set of mechanisms common to all monoamine neurotransmitters. [15] After synthesis, norepinephrine is transported from the cytosol into synaptic vesicles by the vesicular monoamine transporter (VMAT). [ 16 ]
Glutamate is a very major constituent of a wide variety of proteins; consequently it is one of the most abundant amino acids in the human body. [1] Glutamate is formally classified as a non-essential amino acid, because it can be synthesized (in sufficient quantities for health) from α-ketoglutaric acid, which is produced as part of the citric acid cycle by a series of reactions whose ...
Glutamate (the conjugate base of glutamic acid) is abundant in the human body, but particularly in the nervous system and especially prominent in the human brain where it is the body's most prominent neurotransmitter, the brain's main excitatory neurotransmitter, and also the precursor for GABA, the brain's main inhibitory neurotransmitter. [2]