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Primidone, sold under various brand names (including Mysoline), is a barbiturate medication that is used to treat partial and generalized seizures [ 7 ] and essential tremors. [ 8 ] It is taken by mouth. [ 7 ] Its common side effects include sleepiness, poor coordination, nausea, and loss of appetite. [ 7 ]
Barbiturates have largely been replaced by benzodiazepines and nonbenzodiazepines ("Z-drugs") in routine medical practice, particularly in the treatment of anxiety disorders and insomnia, because of the significantly lower risk of overdose, and the lack of an antidote for barbiturate overdose. Despite this, barbiturates are still in use for ...
In general, the safety and effectiveness of alternative medicines have not been scientifically proven [1] and remain largely unknown. [2] Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation , or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life ...
Primidone: may accelerate metabolism of valproate, leading to a decline of serum levels and potential breakthrough seizure. Rifampicin: increases the clearance of valproate, leading to decreased valproate concentrations; Warfarin: valproate may increase free warfarin concentration and prolong bleeding time.
Triazolam is usually used for short-term treatment of acute insomnia and circadian rhythm sleep disorders, including jet lag. It is an ideal benzodiazepine for this use because of its fast onset of action and short half-life. It puts a person to sleep for about 1.5 hours, allowing its user to avoid morning drowsiness.
Clonazepam, sold under the brand name Klonopin among others, is a medication used to prevent and treat anxiety disorders, seizures, bipolar mania, agitation associated with psychosis, obsessive–compulsive disorder, and akathisia. [11] It is a long-acting [12] tranquilizer of the benzodiazepine class. [11]
Novo Nordisk's older weight-loss drug Saxenda helped children between the ages of 6 and under 12 reduce their body mass index by 7.4% in a 56-week trial, according to results presented at a ...
Etifoxine. Etifoxine, sold under the trade name Stresam among others, is a nonbenzodiazepine anxiolytic agent, primarily indicated for short-term management of adjustment disorder, specifically instances of situational depression accompanied by anxiety, such as stress-induced anxiety. [2][6] Administration is by mouth. [7] Side effects ...