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Guanfacine. Guanfacine, sold under the brand name Tenex (immediate-release) and Intuniv (extended-release) among others, is an oral alpha-2a agonist medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure. [3][9] Guanfacine is FDA-approved for monotherapy treatment of ADHD, [3] as well as being used for ...
Sympatholytic. A sympatholytic (sympathoplegic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated by the sympathetic nervous system (SNS). [1] They are indicated for various functions; for example, they may be used as antihypertensives.
Alpha blockers work by blocking the effect of nerves in the sympathetic nervous system. This is done by binding to the alpha receptors in smooth muscle or blood vessels. [37] α-blockers can bind both reversibly and irreversibly. [2] There are several α receptors throughout the body where these drugs can bind.
The nightmares are intense and often horrifying, sometimes lasting well into the day. “There’s a serial killer after me and the last few years I have the same one,” according to a Canadian ...
8% of sudden cardiac death [2] Brugada syndrome (BrS) is a genetic disorder in which the electrical activity of the heart is abnormal due to channelopathy. [2] It increases the risk of abnormal heart rhythms and sudden cardiac death. [2] Those affected may have episodes of syncope. [2] The abnormal heart rhythms seen in those with Brugada ...
Psychiatry. Frequency. c. 4% [1] Nightmare disorder is a sleep disorder characterized by repeated intense nightmares that most often center on threats to physical safety and security. [2] The nightmares usually occur during the REM stage of sleep, and the person who experiences the nightmares typically remembers them well upon waking. [2]
Duloxetine (Cymbalta) Escitalopram (Lexapro) While many antidepressants can cause ED and other intimate dysfunction, some may be more likely than others. SSRIs and SNRIs — two of the most ...
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