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Lupus anticoagulant. Lupus anticoagulant is an immunoglobulin [1] that binds to phospholipids and proteins associated with the cell membrane. Its name is a partial misnomer, as it is actually a prothrombotic antibody in vivo. The name derives from their properties in vitro, as these antibodies increase coagulation times in laboratory tests such ...
Thrombotic thrombocytopenic purpura. Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. [2] This results in a low platelet count, low red blood cells due to their breakdown, and often kidney, heart, and brain dysfunction. [1]
Purpura (/ ˈpɜːrpjʊərə / [1]) is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. [2] They measure 3–10 mm, [3] whereas petechiae measure less than 3 mm, and ecchymoses greater than 1 cm. [4 ...
Two specific types of blood tests are used to aid in the diagnosis of Asherson's syndrome. A coagulation blood test is used to measure and determine the blood's ability to clot and how fast it takes to clot, indicating the presence of lupus anticoagulant in the blood.
Immune thrombocytopenic purpura. Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is an autoimmune primary disorder of hemostasis characterized by a low platelet count in the absence of other causes. [1][2] ITP often results in an increased risk of bleeding from mucosal ...
Purpura fulminans is an acute, often fatal, thrombotic disorder which manifests as blood spots, bruising and discolouration of the skin resulting from coagulation in small blood vessels within the skin and rapidly leads to skin necrosis and disseminated intravascular coagulation. [ 2 ][ 3 ]
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