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Anal fistula is a chronic abnormal communication between the anal canal and the perianal skin. [1] An anal fistula can be described as a narrow tunnel with its internal opening in the anal canal and its external opening in the skin near the anus. [2] Anal fistulae commonly occur in people with a history of anal abscesses. They can form when ...
Goodsall's rule relates the external opening (in the perianal skin) of an anal fistula to its internal opening (in the anal canal). It states that if the perianal skin opening is posterior to the transverse anal line, the fistulous tract will open into the anal canal in the midline posteriorly, sometimes taking a curvilinear course.
Dogs and cats primarily use their anal gland secretions to mark their territory, and generally will secrete small amounts of fluid every time they defecate. Many will often express these glands when anxious or frightened as well. Dogs who are healthy can usually have a wide variety in the appearance of their sac's content. [14]
Several pathologies can present with perianal discharge. Although not exactly the same as rectal discharge, perianal discharge can be misinterpreted as such, given the anatomical proximity. [citation needed] Fistulae draining into the perianal region, as well as pilonidal diseases, are the main entities that fall within this category. Perianal ...
Darvadstrocel, sold under the brand name Alofisel, is a medication used to treat complex perianal fistulas in adults with non-active/mildly active luminal Crohn's disease when fistulas have shown an inadequate response to at least one conventional or biologic therapy. [1] It contains mesenchymal stem cells from fat tissue of adult donors. [2]
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Fistulas can occur in various areas of the human body, and the location of the fistula influences the necessity of the procedure. Some, such as ano-vaginal and perianal fistulas are chronic conditions, and normally will not heal without surgical intervention. [citation needed]
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