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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  3. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    At the same time, loop diuretics inhibit the tubuloglomerular feedback mechanism so that increase in salts at the lumen near macula densa does not trigger a response that reduces the GFR. [6] Loop diuretics also inhibit magnesium and calcium reabsorption in the thick ascending limb. Absorption of magnesium and calcium are dependent upon the ...

  4. Metolazone - Wikipedia

    en.wikipedia.org/wiki/Metolazone

    Metolazone and a loop diuretic will synergistically enhance diuresis over the use of either agent alone. Using this combination, diuretic effects will occur at two different segments of the nephron; namely, the loop diuretic will act at the loop of Henle, and metolazone will act at the distal convoluted tubule. Metolazone is frequently ...

  5. Chlortalidone - Wikipedia

    en.wikipedia.org/wiki/Chlortalidone

    Chlortalidone is considered a first-line medication for treatment of high blood pressure. [2] Some recommend chlortalidone over hydrochlorothiazide. [1] [15] A meta-analysis of randomized controlled trials found that chlortalidone is more effective than hydrochlorothiazide for lowering blood pressure, while the two drugs have similar toxicity.

  6. Hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Hydrochlorothiazide

    Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]

  7. Bowl game schedule today: Breaking down the college football ...

    www.aol.com/bowl-game-schedule-today-breaking...

    The college football bowl schedule doesn't stop for Christmas Eve. San Jose State and South Florida meet in the Hawaii Bowl.

  8. Damian Williams, Manhattan's top federal prosecutor, to ... - AOL

    www.aol.com/news/damian-williams-manhattans-top...

    NEW YORK (Reuters) -Damian Williams, the top federal prosecutor in Manhattan who secured convictions of high-profile defendants including U.S. Senator Bob Menendez and crypto mogul Sam Bankman ...

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